Recently, researchers at Cambridge University have managed to change the blood type of the three dead donor kidneys to universal O. This unprecedented and exceptional breakthrough will allow more transplants to take place, as O's blood type can be used for people with any other blood type, and the researchers' work will soon be published in the British Journal of Surgery.
Professor Mike Nicholson and P.D. Serena McMillan used a standard-thermal infusion machine, a device that connects to the human kidney to run oxygen-rich blood through the organ to better preserve it for future use, and in particular, researchers used it to transmit enzyme-rich blood through the kidneys of a deceased patient.
Serena McMillan says in her statement, "".
It is important to note that all the vessels in our body are receptors that are specific to group A or B. The Ferment used in the study acted like "molecular scissors" by removing blood-type markers that laminate kidney blood vessels. This technique automatically converted the organ into blood group O in just a few hours, because this group does not have specific markers, unlike A and B.
Thus, the transition to "universal" blood type O removes problems of compatibility and rejection. When organs are rejected by the body after transplantation, it is often these markers that are involved in the process. Professor of Transplantology Nicholson explains: "".
The Cambridge team will then study how a new modified kidney with group O will react to the patient's normal blood type with normal blood supply. The infuzion machine allows them to test this method before human clinical trials, and in fact they can inject different types of blood into this kidney of type O and monitor how it reacts by simulating the process of transplantation in the body.
In conclusion, this method of conversion of blood groups to create universal kidneys can increase the availability of kidneys available for transplantation, especially among ethnic minority groups that have less chance of matching most donor kidneys. This change can allow for the replanting of this universal organ to a patient of group A or group B without any restrictions.